Spravato & Ketamine-Assisted Psychotherapy Program (SKAPP)

If you have major depressive disorder (MDD) and found yourself going in circles after trying multiple oral antidepressants, it may be time to consider a different treatment approach.

Understanding Treatment-Resistant Depression (TRD)

If you’ve tried two or more oral antidepressants but still experience depression symptoms, you may be dealing with treatment-resistant depression (TRD).

What is TRD?

Treatment-Resistant Depression (TRD) occurs when individuals with major depressive disorder (MDD) do not achieve adequate relief from their symptoms despite trying two or more antidepressant treatments.

Why Does TRD Happen?

Treatment-Resistant Depression (TRD) has multiple contributing factors, including biological influences like genetics and brain chemistry, as well as psychological challenges such as trauma and chronic stress. Additionally, individual differences in metabolism and medication tolerance can make standard antidepressants less effective.

Treatment Options for TRD

Spravato® (esketamine), an FDA-approved nasal spray for TRD, and ketamine infusions are newer options that offer fast-acting relief for many who do not respond to traditional treatments.

What is Spravato®?

Spravato® is a prescription medication used alongside an oral antidepressant to help treat:

  • Adults with treatment-resistant depression (TRD)
  • Depressive symptoms in adults with major depressive disorder (MDD) who experience suicidal thoughts or behaviors

Watch the video below to learn more about Spravato®:

At Best Fit Counseling & Psychiatry in Ann Arbor, Michigan, we offer Spravato & Ketamine-Assisted Psychotherapy Program (SKAPP) as a cutting-edge treatment option for individuals struggling with treatment-resistant mental health conditions.

Our SKAPP Process

At Best Fit Counseling & Psychiatry, our approach to mental health combines the strengths of psychiatry and therapy to provide comprehensive care. We focus on integrating medication management, psychotherapy, and holistic wellness strategies to address the unique needs of each individual.

01.

Initial Consultation

A thorough assessment to determine suitability for ketamine-assisted therapy, including medical history review, treatment expectations, and discussion of mental health goals.

02.

Preparation

Pre-session guidance and support to ensure you’re mentally and physically prepared for the ketamine experience, promoting a safe, focused, and effective treatment journey.

03.

Administration

Medically supervised ketamine infusions administered in a controlled environment, aimed at providing rapid relief from depression, suicidal ideation, anxiety, PTSD, and others.

04.

Integration Therapy

Post-session psychotherapy to help process and integrate the ketamine experience, enhancing therapeutic outcomes, personal growth, and promoting long-term mental health.

Our medication rooms

Our medication room is designed to provide a safe, comfortable, and welcoming environment that supports healing and well-being. Every detail, from calming decor to supportive amenities, is thoughtfully chosen to ensure patients feel respected, secure, and genuinely cared for.

  1. Air Purifier – Filters the air, removing allergens and impurities to create a fresh, clean atmosphere.
  2. Dimmable Lights – Adjustable lighting to help create a calming environment and reduce sensory overstimulation.
  3. Comfortable Recliner – Provides physical comfort and support for patients during extended sessions.
  4. Support Person Chair – Allows companions to be present, offering additional emotional support for patients.
  5. Sleep Mask – Helps patients relax by blocking out light, enhancing calm and focus during treatment.
  6. Curated music for Spravato – Curated with relaxing music/ playlist to enhance mood and encourage relaxation.
  7. Noise-Canceling Headphones – Reduces external sounds to deepen relaxation and provide a private experience.

8. Mint/Candy for Nausea – Eases nausea, a possible side effect of ketamine, making the session more comfortable.
9. Drinking Water – Keeps patients hydrated and comfortable, helping alleviate dry mouth or mild dehydration.
10. Hand Sanitizer – Provides quick access for hand hygiene, ensuring a clean, sterile environment.
11. UV Lamp – Disinfects surfaces, reducing the risk of infection and maintaining high hygiene standards.

12. Air Conditioning Unit with Temperature Control – Maintains the room at a comfortable temperature for patient ease.
13. Weighted Blankets – Adds comfort and grounding, especially for anxious or restless patients.
14. Low-Stimulus Artwork / Nature Posters – Creates a peaceful, visually soothing atmosphere without overstimulation.
15. Indoor Plants – Adds a natural, calming element while improving air quality and providing visual comfort.
16. Tissue Box – Accessible tissues for patient use, ideal for any emotional or mild physical side effects.

Our Waiting Room

Research that support Spravato & Ketamine-Assisted Psychotherapy Program (SKAPP)

On March 5, 2019, the Food and Drug Administration (FDA) approved the first new medication for major depression in decades. The drug is a nasal spray called esketamine, derived from ketamine—an anesthetic that has made waves for its surprising antidepressant effect...
The U.S. Food and Drug Administration approved Spravato (esketamine) nasal spray, in conjunction with an oral antidepressant, for the treatment of depression in adults who have tried other antidepressant medicines but have not benefited from them (treatment-resistant depression)...
More recently, ketamine has been widely used for treatment-resistant depression (TRD) — that is, severe depression that has not improved with several other therapies, including people who are experiencing suicidal thoughts...
Major depressive disorder (MDD) affects more than 16 million adults each year in the United States. Ketamine is one agent that has received attention as a potential fast-acting and effective treatment for patients with MDD with suicidal ideation (MDSI) and for those with TRD...

Watch Yale Medicine's insightful video exploring the use of ketamine as a treatment for depression.

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Frequently Asked Questions

Spravato is the brand name for esketamine, a prescription nasal spray developed by Janssen Pharmaceuticals. It is a derivative of ketamine and is used to treat treatment-resistant depression in adults. Spravato works by targeting the NMDA receptor in the brain, which is thought to help alleviate depressive symptoms.

Spravato & Ketamine-Assisted Psychotherapy Program (SKAPP) is a specialized treatment program that combines the therapeutic effects of Spravato (esketamine) or ketamine with structured psychotherapy sessions. SKAPP is designed to support individuals with various mental health conditions, such as treatment-resistant depression, PTSD, anxiety disorders, and suicidal ideation.

Through a combination of medication and guided therapy, SKAPP aims to provide relief from symptoms, enhance mental resilience, and promote long-term mental health by helping patients process and integrate their experiences in a supportive environment.

Yes, Spravato & Ketamine-Assisted Psychotherapy Program (SKAPP) at Best Fit Counseling & PsychiatrySpravato & Ketamine-Assisted Psychotherapy Program (SKAPP) is safe. We administer ketamine in a controlled, clinical setting by our trained professionals. Our team closely monitors patients throughout the treatment to ensure their safety and well-being.

Spravato & Ketamine-Assisted Psychotherapy Program (SKAPP) is suitable for individuals who have not responded to traditional treatments for major depressive disorder (MDD), suicidal ideation, anxiety, PTSD, and OCD. A thorough assessment by our clinical team will determine if SKAPP is appropriate for you. Contact us at 734-412-7300 to learn more about our Spravato & Ketamine-Assisted Psychotherapy Program.

emergency hotlines

If you or someone you know is experiencing a mental health emergency in the United States, it’s crucial to seek immediate help.

988

Contact the National Suicide Prevention Lifeline via call or text for 24/7 emotional support.

741741​

For emotional distress, text HOME to get immediate help from a Crisis Text Line counselor.

911

For life-threatening emergency or urgent medical situations, dial 911 right away.

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